Expression of Osteoarthritis of the Knee in a Modern Cadaver Sample

Ashley Ronvik University of Indianapolis
Faculty Sponsor(s): Stephen Nawrocki University of Indianapolis
The most common type of arthritis seen in humans and other vertebrates is degenerative arthritis, more commonly known as osteoarthritis (OA). OA is produced by the slow breakdown of cartilage between the bones that come together to make a joint, eventually allowing the bones to come into direct contact. The resulting pain can be debilitating. On dry bone, OA can be diagnosed by the formation of osteophytes, marginal lipping of the joint boundaries, and eburnation of the subchondral surface in later phases. My research addresses whether the age and sex of an individual affects the degree of OA in the knee joint. I began by examining a sample of two dozen dry bone specimens in the Osteology Laboratory at UIndy. Looking at the joint surfaces of the distal femur, proximal tibia, and patella. These specimens allowed me to train myself in identifying the main diagnostic features of OA and I developed a simple ordinal ranking system to reflect which cases are worse than others. I then moved on to looking at a sample of eighteen modern male and female cadaver specimens in the Gross Anatomy Laboratory at UIndy. I was able to identify the presence and severity of OA in the sample by dissecting and comparing the knees of the cadavers. My presentation will outline the results of this examination and address whether sex or age at death had an impact on the degree of OA expressed at the knee joint.
Biology
Oral Presentation

When & Where

12:30 PM
Gallahue Hall 101