9. Medication Patterns among Infants and Toddlers with Neurodevelopmental Syndromes

Kayla Kollmann Purdue University West Lafayette, Joey Shin Purdue University West Lafayette, Liberty-Ann Shelton Purdue University West Lafayette, Patricia Aguilar Purdue University West Lafayette
Faculty Sponsor(s): Nicole Witthuhn Purdue University West Lafayette, Bridgette Tonnsen Purdue University West Lafayette
Children with Neurogenetic Syndromes (NGS) display a variety of symptoms that may be managed with medication use. These symptoms include physical, cognitive and developmental delays with additional medical issues that originate from these delays. In the present study, we examine three NGS groups, Angelmans (AS), Williams (WS) and Prader-Willi Syndromes (PWS). We sought to understand the differences in medication use by these NGS populations and how usage may change with development. We hypothesize that the number of medications utilized between the NGS groups will vary significantly, with PWS demonstrating the most use due to early intervention strategies that emphasize medication. We hypothesize that there will be a significant increase in medication use in older participants than younger due to developing or worsening symptomologies. Participants included 98 children (AS=35; WS=34; PWS=29) with reported current medication use as part of the Purdue Early Phenotype Survey, a longitudinal study to examine the developmental markers of NGS populations. The ages of these participants from a single assessment datapoint ranged from 6 to 58 mo. Final statistical analyses will include Wilcoxon and Omnibus testing to investigate statistical differences in the number of medications utilized between each NGS group as well as the relationship between the number of medications and age. This study addresses the lack of literature surrounding medication patterns in NGS populations, providing comparison of medication usage and the related age trend among these NGS groups. Future research includes examining effectiveness of medication type and necessary dosage regimens.
Poster Presentation

When & Where

Irwin Library Lower Level